I-309嗜酸粒細(xì)胞趨化蛋白CCL1抗體相關(guān)標(biāo)記     Alexa Fluor 350   Alexa Fluor 488   Alexa Fluor 555   Alexa Fluor 647   AP   APC   Biotin   Cy3   Cy5  
Cy5.5   Cy7   FITC   Gold   HRP   PE   PE-Cy3   PE-CY5   PE-CY5.5   PE-CY7   RBITC  
英文名稱    I-309
中文名稱    嗜酸粒細(xì)胞趨化蛋白CCL1抗體
別    名    C-C motif chemokine 1 precursor; chemokine (C-C motif) ligand 1; BF534335; I-309; Scya1; CCL1; Chemokine CC Motif Ligand 1; inflammatory cytokine I-309; P500; SCYA1; SISe; small inducible cytokine A1; T lymphocyte secreted protein I-309; TCA3.
研究領(lǐng)域    細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo) 
抗體來源    Rabbit
克隆類型    Polyclonal
交叉反應(yīng)    Human, Mouse, Rat, Pig, Rabbit, 
I-309嗜酸粒細(xì)胞趨化蛋白CCL1抗體產(chǎn)品應(yīng)用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量    10kDa
細(xì)胞定位    分泌型蛋白 
性    狀    Lyophilized or Liquid
濃    度    1mg/1ml
免 疫 原    KLH conjugated synthetic peptide derived from human CCL1 (12-30aa)
亞    型    IgG
純化方法    affinity purified by Protein A
儲(chǔ) 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存條件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed    PubMed
產(chǎn)品介紹    background:
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8. [provided by RefSeq, Jul 2008].

Function:
Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8.

Subunit:
Monomer.

Subcellular Location:
Secreted.

Similarity:
Belongs to the intercrine beta (chemokine CC) family.

Gene ID:
6346

Database links:
Entrez Gene: 6346 Human
Omim: 182281 Human
SwissProt: P22362 Human
Unigene: 72918 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

CCL1屬于CC趨化因子家族，是由活化的T細(xì)胞分泌的糖蛋白。CCL1是一小分子的細(xì)胞因子C與細(xì)胞表面的趨化因子受體CCR8結(jié)合,對(duì)單核細(xì)胞，自然殺傷細(xì)胞，未成熟的B細(xì)胞和樹突狀細(xì)胞有細(xì)胞趨化作用.