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IP 10 Human, His/ 重組人IP-10（CXCL10）, His

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IP 10 Human, His/ 重組人IP-10（CXCL10）, His 產(chǎn)品編號(hào)：CHM-346
產(chǎn)品規(guī)格：5μg/25μg/1mg

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IP 10 Human, His/ 重組人IP-10（CXCL10）, His

產(chǎn)品編號(hào)：CHM-346
產(chǎn)品規(guī)格：5μg/25μg/1mg
 

Synonyms Small inducible cytokine B10, CXCL10, 10 kDa interferon-gamma-induced protein, Gamma-IP10, IP-10, chemokine （C-X-C motif） ligand 10, C7, IFI10, INP10, crg-2, mob-1, SCYB10, gIP-10.
Introduction Chemokine （C-X-C motif） ligand 10 （CXCL10） is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein （?-IP10 or IP-10）. CXCL10 is secreted by several cell types in response to IFN-?. These cell types include monocytes, endothelial cellsand fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytesand T cells, promotion of T cell adhesion to endothelial cells, anti tumor activity, and inhibition of bone marrow colony formation and angiogenesis. The gene for CXCL10 is located on human chromosome 4in a cluster among several other CXC chemokines. This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3. The three-dimensional crystal structure of this chemokine has been determined under 3 different conditions to a resolution of up to 1.92A.
Description IP-10 His Tag Human Recombinant ?produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 77 amino acids fragment （22-98） and having a total molecular mass of 8.5 kDa with an amino-terminal hexahistidine tag.
The IP-10 His is purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered clear solution.
Formulation IP-10 His is supplied in 10mM Tris HCl pH8, 1mM EDTA and 50% glycerol.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.
Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.


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