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Omentin Human/ 人網(wǎng)膜素

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Omentin Human/ 人網(wǎng)膜素 產(chǎn)品編號：CYT-301
產(chǎn)品規(guī)格：2μg/10μg/1mg

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Omentin Human/ 人網(wǎng)膜素

產(chǎn)品編號：CYT-301
產(chǎn)品規(guī)格：2μg/10μg/1mg
 

Synonyms Inectin-1, HL1, LFR, HL-1, INTL, ITLN, hIntL.
Introduction Omentin is a recently recognized gene highly localized to the mental tissue （visceral adipose tissue）. Omentin is present in the stromal vascular cells in the adipose tissue rather than in the adipocytes. Omentin is predominantly expressed in the visceral adipose tissue than the subcutaneous tissue, with the omentin mRNA being 150 times higher in the visceral adipose tissue. Omentin has also been detected in human blood using western blot analysis, and seems to increase insulin-stimulated glucose uptake in 3T3-L1 adipocytes in mice. Omentin seems to increase Akt phosphorylation irrespective of insulin presence. Its role in glucose metabolism and obesity remains to be described; an insulin-sensitizing action is possible.Differences in Omentin expression has been noted in adipose tissue from normals and patients with inflammatory bowel disease although its significance is unknown.
Description Omentin Human Recombinant is produced in E.Coli by recombinant DNA technology is a single, polypeptide chain containing 313 amino acids and having a molecular mass of
35 kDa. Inectin is purified by proprietary chromatographic techniques.
Source E.Coli.
Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder.
Formulation Each mg of lyophilized powder contains 5mM sodium phosphate buffer pH-7.5 and 0.5% manntiol.
Solubility It is recommended to reconstitute the lyophilized Omentin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions.
Stability Lyophilized Inectin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Inectin should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles.
Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE.
Amino acid sequence MNQLSFLLFL IATTRGWSTD EANTYFKEWTCSSSPSLPRS CKEIKDECPS AFDGLYFLRT ENGVIYQTFC DMTSGGGGWT LVASVHENDM RGKCTVGDRW SSGSKADY PEGDGNWANY NTFGSAEAAT SDDYKNPGYY DIQAKDLGIW HVPNKSPMQH WRNSSLLRYR TDTGFLQTLG HNLFGIYQKY PVKYGEGKCW TDNGPV*V YDFGDAQKTA SYYSPYGQRE FNNERAANAL CAGMRVTGCN TEHHCIGGGG YFPEASPC GDFSGFDWSG YGTHVGYSSS REITEAAVLLFYR.
Applications Elisa
Western blot.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.


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