Rabbit  Anti- PAR-1抗體說(shuō)明書(shū)

Catalog Number : RS-0828R     
Quantity size :   0.1ml  （dilute with pH 7.4    0.01 M PBS or antibody diluent ）

Background:

Thrombin receptor is a 7 transmembrane G protein coupled receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. It may play a role in plaet activation and in vascular development. Thrombin receptor expression has been documented in various blood cells, colon, kidney, liver, lung, skin, and vessel. ESTs have been isolated from adrenal, embryo, heart, heart/melanocyte/uterus, liver/spleen, pineal, skin, spleen, and vessel.

Function : High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in plaets activation and in vascular development.

pecificity :   

–     Anti- PAR-1 is a rabbit monoclonal antibody unconjugated                

–     specific for PAR-1 of  mo，hu        

–     use for western blotting,elisa,immunoprecipitation and immunohistochemistry

–     Protein G affinity chromatography purification, purity :>95%

–     Isotype:  IgG

–     mol wt:  84kDa

Application :  

–     Western blotting 1:100-500                

–     Immunohistochemistry 1:100-500                 

–     ELISA 1:500-1000                  

–     Optimal working dilutions must  be determined by the end user.

Storage:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at least six weeks at 2-4 ℃

Important Note: This product as supplied is intended for research use only, not for use in  human, therapeutic or diagnostic applications.

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