Rabbit Anti-GLU-2抗體說明書

FROM:Santa Cruz

Catalog Number : Rs-35702R

Quantity Size : 0.2ml （dilute with pH 7.4  0.01 M PBS or antibody diluent ）

Background: GLU-2 plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. GLU-2 permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia （CLAH）, also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode distinct isoforms.

Specificity :  · anti-GLU-2 is a rabbit monoclonal antibody unconjugated

· specific for GLU-2 of human, mouse, rat

· broadly reactive with mammalian species

· epitope mapping near the amino terminus of GLU-2 of human, mouse, rat

· use for western blotting, elisa, immunoprecipitation

and immunohistochemistry

· Protein G affinity chromatography purification, purity :>95%

· Isotype: IgG

· mol wt: 32kDa

Application : · Western blotting 1:100-500

· Immunohistochemistry 1:100-500

· ELISA 1:500-1000

· Optimal working dilutions must be determined by the end user

Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4 ºC.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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