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Anti-Integrin beta 5/FITC,FITC標(biāo)記的整合素β5抗體

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研盟生物標(biāo)記抗體“Anti-Integrin beta 5/FITC,FITC標(biāo)記的整合素β5抗體“，規(guī)格100ul，保證品質(zhì)，咨詢：

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產(chǎn)品名稱 Anti-Integrin beta 5/FITC,FITC標(biāo)記的整合素β5抗體

產(chǎn)品編號 BYK-2094R-FITC

英文名稱 Anti-Integrin beta 5/FITC

中文名稱 FITC標(biāo)記的整合素β5抗體

別名 Integrin beta 5; Integrin beta-5; integrin, beta 5; ITB5_HUMAN; Itgb5; AA475909; AI874634; beta-5; beta5; ESTM23; [b]-5; [b]5; [b]5A; [b]5B) FLJ26658; ITGB 5; ITGB5;

研究領(lǐng)域細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  細(xì)胞骨架
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow,
產(chǎn)品應(yīng)用 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分子量 86kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免疫原 KLH conjugated synthetic peptide derived from human Integrin beta 5

亞型 IgG
純化方法 affinity purified by Protein A
儲存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-Integrin beta 5/FITC,FITC標(biāo)記的整合素β5抗體產(chǎn)品介紹：Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function. The integrin subunit beta 5 has only been associated with the alpha v subunit to form the alpha v beta 5 heterodimer. This integrin mediates cell adhesion to vitronectin and also recognizes fibronectin when the integrin is activated. This integrin is found in a variety of cells in most normal tissue.

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