Rabbit anti-ADRB2, FITC conjugated
（CD63 antigen isoform A）
Catalog Number : RSF-1063R
Quantity size : 0.2ml （2mg/ml; Reconstitute with 0.5 ml of sterile distilled water.）
Background: Beta 2 Adrenergic Receptor is a member of the G protein coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L type calcium channel Ca（V）1.2. This receptor channel complex also contains a G protein, an adenylyl cyclase, cAMP dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel.
Specificity :
· anti- ADRB2 is a rabbit polyclonal antibody, FITC conjugated
· specific for ADRB2 of human, mouse and rat
· epitope mapping near the amino terminus of ADRB2 of human,
mouse rat, pig origin
· human, mouse rat pig cross reacted
· affinity chromatography purification, purity :>95%
· Isotype: IgG
· mol wt: 25kDa
Rabbit anti-ADRB2, FITC conjugated
Application :
· FCM: 1:20-100
· Immunohistochemistry : 1:20-200
· Immunocytochemistry: 1:20-200
· Excitation spectrum: 490-495nm
· Emission spectrum: 520-530nm
· Optimal working dilutions must be determined by the end user.
Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4 ºC.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Rabbit anti-ADRB2, FITC conjugated
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